McGaugh (2000)

Memory--a Century of Consolidation

Science, 287(5451), 248-251

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Abstract

The memory consolidation hypothesis proposed 100 years ago by Müller and Pilzecker continues to guide memory research. The hypothesis that new memories consolidate slowly over time has stimulated studies revealing the hormonal and neural influences regulating memory consolidation, as well as molecular and cellular mechanisms. This review examines the progress made over the century in understanding the time-dependent processes that create our lasting memories.

Reference

McGaugh, J. L. (2000). Memory: A century of consolidation. Science, 287(5451), 248-251.

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Consolidation Memory Processes

Definition

Consolidation is the hypothesis, first proposed by Müller and Pilzecker a century ago, that new memories are fragile at first and become stable only gradually through time-dependent processes after learning