Byrne & Hawkins (2015)

Nonassociative Learning in Invertebrates

Cold Spring Harbor Perspectives in Biology, 7(5), a021675

Find It

DOI

Reference

Byrne, J. H., & Hawkins, R. D. (2015). Nonassociative Learning in Invertebrates. Cold Spring Harbor Perspectives in Biology, 7(5), a021675. https://doi.org/10.1101/cshperspect.a021675

What Rests on This

1 mechanism cites this source. Each finding below is quoted as it appears on that mechanism's own page.

Non-Associative Learning Memory Systems

Definition

Sensitization is the strengthening of a response by strong or repeated stimulation; both it and habituation count as non-associative because they need only the stimulus itself, with no pairing of one event with another as in conditioning
Neural substrate

Sensitization works through serotonin released by facilitatory interneurons, which acts via cAMP/PKA and PKC signaling at the same sensory-motor synapse; long-term sensitization additionally needs CREB-regulated gene transcription and new protein synthesis